Description : |
Interleukin-12 is a disulfide-linked heterodimeric protein (p70),
composed of two subunits, p35 and p40, which are encoded by two different genes.
Accumulating data indicate that p40 secretion precedes that of IL-12 expression.
In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to
p19 to form IL-23. Recombinant murine IL-12 p40 is a 40 kDa protein containing 313 amino acid residues.
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Catalog #: |
001-MIL12P40 |
Source : |
CHO cells (Chinese Hamster Ovarian Cells) |
Formulation : |
The sterile filtered solution was lyophilized from 1 x PBS, pH 7.2. |
Stability : |
The lyophilized protein is stable for a few weeks at room temperature, but best stored at Ð800C .
Reconstituted IL-12 p40 should be stored in working aliquots at Ð800C .
|
Purity : |
Greater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
Reconstitution : |
We recommend a quick spin followed by reconstitution in 1 x PBS,
pH 7.2 to a concentration of 0.1-1.0 mg/ml. This solution can then
be diluted into other aqueous buffers and stored at 40C
for 1 week or Ð800C for future
use.
|
Biological Activity : |
Murine IL-12 p40 has no IL-12 (p70) antagonist activity.
|
PubMed Link : |
IL-12 p40 Murine |
Usage: |
For research only. Not for use in diagnostic or therapeutic procedures. |
Country of Origin : |
USA |
Experience - Innovation - Persistence
