Description : |
Transforming Growth Factor-beta3 (TGF-beta3) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta3 is a 25.0 kDa protein with each subunit containing 112 amino acid residues. |
Catalog #: |
002-TGF3 |
Source : |
A293 cells |
Formulation : |
Lyophilized from Sodium Citrate, pH 3.5 buffer. |
Stability : |
The lyophilized protein is stable for a few weeks at room temperature, but best stored at -200C. Reconstituted TGF-beta3 should be stored in working aliquots at -200C. |
Purity : |
Greater than 98% by SDS-PAGE and HPLC analyses.
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
|
Reconstitution : |
We recommend a quick spin followed by
reconstitution in water to a concentration of 50 ug/ml. This
solution can then be stored at 40C
for 1 month. It is recommended that further dilutions be made
in PBS containing 2mg/ml albumin and stored at -800C.
|
Biological Activity : |
Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED50 was found to be <0.05ng/ml, corresponding to a specific activity of >2 x 108 units/mg. |
AA Sequence : |
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
|
PubMed Link : |
TGFbeta3 |
Usage: |
For research only. Not for use in diagnostic or therapeutic procedures. |
Country of Origin : |
USA |
Experience - Innovation - Persistence
