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Cell Culture

We have established ourselves as a premier supplier of high quality reagents for the biomedical industry. SBH Sciences' experience and technical expertise has enabled us to commercially produce highly purified:

Cytokines

  • Recombinant proteins

Enzymes

  • Glycosyltransferase

Monoclonal Antibodies

  • Anti-Cytokine
  • Anti-Carbohydrate

We have developed in-house over 70 cell-culture-derived products including; 30 recombinant cytokines, 8 enzymes, and are an industry source for:

Activin-a   HGF  IL-23 
BMP-2  IFN-b  sIL-6R 
BMP-7  IL-12   

In addition, SBH Sciences produces highly pure naturally expressed human MIC-1 which is available for the R&D market. SBH Sciences' human GDF-15/MIC-1 is a soluble disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains (25,000 MW). SBH Sciences is looking for partners to investigate human MIC-1 as a therapeutic agent, as well as a diagnostic tool.

We specialize in:
Protein Expression, Purification, and Mid-scale Production

  • Cell culture of mammalian and insect cells, serum-free media optimization, adaptation to suspension, production of lysates
  • Transient and stable mammalian cell transfection, cloning, sub-cloning
  • Follow clients SOP's for expression of their product
  • Manipulation of customers cell line to improve expression
  • Capability to work with mammalian or insect cells in roller bottles or spinner flasks

We offer a broad range of discovery research services including:

  • production and purification of biologics (Cell Culture, Protein Purification)
  • detection and quantification of  these substances (ELISA, HPLC)
  • screening for biological or cytotoxic activity (cell-based bioassays, Receptor-based binding assay, or custom designed assays)
  • Formulation and stability studies (e.g. temperature and matrix effect)
  • Development of ADA (Anti-Drug Antibody assay)

Let us help you:

  • Streamline your process
  • Reduce your development time
  • Increase your yields while maintaining exceptional purity
  • Reduce production costs
SBH Sciences welcomes inquiries from those seeking a dependable resource and collaborator in developing pharmaceutical and biotechnology-derived products.


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Discovery Research Products & Services
(508) 650-6218 | Info@SBHsciences.com
The World's Leading Provider of Cytokine Cell-Based Assays