O-Linked Glycosylation Toolkit
SBH Sciences offers a portfolio of tools for studying O-linked glycosylation, including highly active glycosyltransferase enzymes for building glycan structures on peptides or proteins, as well as monoclonal antibodies specific to the glycan structures.
We currently offer 8 recombinant glycosyltransferase enzymes:
To learn more about these important enzymes and O-glycosylation in general, please visit the Glycosyltransferase Enzymes page. To learn more about each enzyme in particular, please click on each enzymes name above.
We currently offer 3 monoclonal anti-carbohydrate antibodies, to carbohydrate antigens that are highly up-regulated in cancerous tissues:
To learn more about the Tn, STn, T and other carbohydrate-based, cancer-specific antigens, please visit the Carbohydrate Cancer Antigens page. To learn more about the specific antibodies, please click on each antibody name above.
We also offer a Biotin-MUC1 Peptide, that can act as an acceptor substrate for the GalNAc-transferases T2, T3 & T5. In conjunction with our Anti-Tn, an activity assay can be constructed to monitor GalNAc-T activity in protein fractions. Please click on the peptide name for more details.
We will be adding new products soon, including GalNAc-T4, GalNAc-T7, GalNAc-T11, GalNAc-T12, and GalNAc-T14 eznymes.
SBH Sciences is looking for partners to investigate our glycosyltransferase enzymes and carbohydrate antibodies as diagnostic tools, therapeutics or for production of glycol-peptide/glycol-protein products. Moreover, our extensive bioassay and in vitro biomarker analysis capabilities are available to support development of your product.
We are open for suggestions and would be pleased to hear from you.
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