Cell Based Assay Services

"SBH Sciences has been a crucial partner in our journey from concept to IND. Their support was critical as we developed and executed novel mechanistically intricate oncology assays, allowing the screening of thousands of compounds."

David Warshawsky, Founder/CEO
Vuja De Sciences

At SBH Sciences, we are continually developing new assays for our customers and would be pleased to include additional ones at your request. We can assure strict confidentiality and superior execution which will be delivered in a time and cost effective manner. The expected turnaround time per assay is less than two weeks, and includes a written report containing methods, results, and conclusions. SBH Sciences is determined to maintain the highest standards and deliver the highest quality products and services. We welcome your suggestions and encourage you to communicate with us about your individual research requirements.

When the need arises to analyze the activity of novel compounds or neutralization capability of your antibody or receptor, please contact us. It will be our pleasure to assist you.

The Most Comprehensive Cytokine and Chemokine Assay Capabilities Worldwide

SBH Sciences excels in the development and validation of cell-based assays for cytokines and chemokines and is proud to offer 360 bioassays. In addition to the cytokine bioassays listed below, we have developed additional bioassays for Canine, Equine, Feline, Porcine, Rhesus Macaque and Swine derived cytokines. Each of our assay can be also used to determine neutralization capability of antibodies and receptors. We are also offering binding assays for all those cytokines.

Cell Phenotyping

Proliferation

Cytotoxicity

Cell Migration & Invasion

Phagocytosis

Immune Function

T-Cell Activation

PBMC Stimulation

Microglial Activation

Complement-Dependent Cytotoxicity (CDC)

Antibody-Dependent Cellular Cytotoxicity (ADCC)

Antibodies & Biologics

Neutralizing Antibody Assays

Anti-Drug Antibody (ADA) Assays

BiTE (Bi-Specific T-Cell Engager) Assays

Antibody Drug Conjugate (ADC) Assays

Target Engagement

Agonist/Antagonist Screening

Receptor-Ligand Binding Assays

GPCR Activation Assays

Chemokine Functional Assays (GPCR-Based)

Biomarkers & Proteins

Immunoassays

Lumit™ Immunoassays

Cytokine Release Assays

Translational Models

Organoid Models (in collaboration with Bonds Biosystems)

Cytokine	Human	Murine	Rat	Bovine
4-1BBL	+ (data)
Activin A	+ (data)	+	+
Activin B	+ (data)
Adipolean / gArcp30	+ (data)	+
Adiponectin	+
AITRL	+ (data)
Amphiregulin	+ (data)	+ (data)
APRIL	+
ApoE2	+ (data)
ApoE3	+ (data)
ApoE4	+(data)
ANG-1	+
Artemin	+	+ (data)
B7-1		+
BAFF	+ (data)
BAFF- Receptor	+ (data)
BDNF	+ (data)	+ (data)	+ (data)
Betacellulin	+	+
BMP-2	+	+	+
BMP-3	+
BMP-4	+ (data)	+
BMP-5	+
BMP-6	+ (data)
BMP-7	+ (data)	+ (data)	+ (data)
BMP-9 / GDF-2	+
BMP-10	+
BMP-13 / CDMP-2 / GDF-6	+
BMP-14 / CDMP-1 / GDF-5	+	+
Cardiotrophin-1	+	+
CD22	+
CD30 Ligand	+
CD40 Ligand	+ (data)
Chemerin	+
COCO	+
CNTF	+		+
CTGF	+
CTGFL / WISP-2	+
CYR61	+
DHH (Desert Hedgehog)	+
DKK-1	+
EG-VEGF	+	+
EGF	+ (data)	+ (data)	+
EGF-R-Fc	+
EMAP-II	+
Endostatin	+
Epigen	+ (data)
Epiregulin	+
EPO	+ (data)	+ (data)
Fas	+
Fas-Ligand	+ (data)
FGF-acidic	+	+
FGF-basic	+ (data)	+ (data)	+ (data)	+ (data)
FGF-4	+ (data)
FGF-5	+ (data)
FGF-6	+ (data)
FGF-7 / KGF	+ (data)	+
FGF-8	+ (data)
FGF-8a	+(data)
FGF-9	+ (data)	+
FGF-10	+
FGF-16	+ (data)
FGF-17	+
FGF-18	+ (data)
FGF-19	+ (data)
FGF-20	+
FGF-21	+ (data)
FGF-23	+ (data)	+
FGF-R1 / Fc Chimera	+
FGF-R4 / Fc Chimera	+
Fibronectin	+
Flt3/ Fc Chimera	+
Flt3-Ligand	+ (data)	+ (data)
Follistatin	+
Fractalkine	+		+
sFRP-1	+
G-CSF	+ (data)	+	+
Galectin-3	+
GASP-1	+
GDF-3	+
GDF-9	+
GDF-9B	+
GDF-11	+ (data)
GDNF	+ (data)	+ (data)	+ (data)
GH (Growth Hormone)	+ (data)
GM-CSF	+ (data)	+(data)	+	+
Gremlin-1	+ (data)
GRO-alpha / MGSA (CXCL1)	+
GRO-beta	+
GRO-gamma	+
GRO-KC			+
HB-EGF	+ (data)
Heregulin-beta 1	+ (data)
HGF	+ (data)	+
HVEM-Fc	+
IFN-a	+ (data)	+
IFN-a -R2-FC	+
IFN-b	+ (data)
IFN-g	+ (data)	+		+
IFN-g-RII	+
IFN-ω	+ (data)
IGF-I	+ (data)	+ (data)	+
IGF-II	+ (data)
IGF-Binding Protein 1	+
IGF-Binding Protein 2	+ (data)
IGF-Binding Protein 3	+ (data)
IGF-Binding Protein 4	+
IGF-Binding Protein 5	+
IGF-Binding Protein 6	+ (data)
IGF-Binding Protein 7	+
IL-1a	+ (data)	+	+
IL-1b	+ (data)	+	+	+
IL-1-Receptor Antagonist	+
IL-1-sReceptor II	+
IL-2	+ (data)	+	+
s-IL-2 Receptor alpha	+
IL-2R Beta	+
IL-3	+ (data)	+ (data)	+
s-IL-3 Receptor alpha	+
IL-4	+ (data)	+	+	+
s-IL-4 Receptor alpha	+
IL-5	+ (data)	+ (data)	+
s-IL-5 Receptor alpha	+
IL-6	+ (data)	+	+
s-IL-6 Receptor	+
IL-7	+ (data)	+	+
IL-7-R alpha / Fc Chimera	+
IL-8	+
IL-9	+ (data)	+
IL-10	+ (data)	+	+
IL-10 Receptor alpha	+
IL-11	+ (data)	+
IL-12 p70	+	+	+
IL-12 p80		+
IL-13	+ (data)	+	+	+
IL-15	+ (data)	+(data)	+
IL-16	+	+
IL-17	+	+
IL-17B	+
IL-17D	+
IL-17E		+
IL-17F	+
IL-18	+	+
IL-18-BPa / Fc Chimera	+
IL-19	+
IL-20	+
IL-21	+ (data)	+
IL-22	+	+
IL-22BP	+
IL-23	+ (data)	+
IL-24	+
IL-27	+ (data)
IL-33	+ (data)	+
IL-35	+
IL-36 beta	+	+
IL-36 gamma	+
Insulin	+ (data)			+
IP-10	+
Klotho	+ (data)	+
LAG-3	+
Leptin	+	+	+
LIF	+ (data)	+ (data)
LIGHT	+	+
M-CSF	+ (data)	+	+
Maspin	+
MCP-1	+
MCP-2	+
MCP-3	+
MCP-4	+
MIA	+
MIC-1 / GDF-15	+
MIF	+
MIP-1 alpha	+
MIP-2		+
Myostatin	+ (data)	+
Myostatin-Propeptide	+ (data)	+
Nanog	+
Neuropoietin		+
Neuroserpin	+ (data)	+
Neurturin	+
b-NGF	+ (data)	+ (data)
NGF-Receptor / Fc Chimera	+
Noggin	+ (data)	+ (data)
NOV	+ (data)
NT-3	+
NT-4	+
Oncostatin M	+ (data)
OTOR	+
OX40-Ligand	+
PDGF-AA	+ (data)	+
PDGF-AB	+ (data)
PDGF-BB	+ (data)
PDGF-CC	+ (data)
PDGF-DD	+
PF-4	+
Persephin		+
Prokineticin-2	+
R-Spondin-1	+ (data)	+
R-Spondin-2	+
R-Spondin-3	+
RANK Ligand		+
SCF	+ (data)	+ (data)	+
SCGF-A	+	+	+
SCGF-B	+	+	+
Sonic Hedgehog	+ (data)	+
SOST-1	+
TGF-a	+ (data)
TGF-b1	+ (data)
TGF-b-RI	+
TGF-b-RII	+
TGF-b2	+ (data)
TGF-b3	+ (data)
TL-1A	+	+
TNF-a	+ (data)	+	+	+
TNF-b	+ (data)
sTNF- r I	+
sTNF-r II	+ (data)
TPO	+ (data)	+ (data)
Trail / Apo2 Ligand	+
sTrail Receptor-1	+
sTrail Receptor-2	+
TrkA / Fc Chimera	+
Tweak	+ (data)
Tweak Receptor	+
Twisted Gastrulation (TSG)	+ (data)	+
USAG-1	+
VEGF - 121	+ (data)
VEGF - 165	+ (data)	+	+
VEGF - B	+ (data)
VEGF - C	+ (data)
VEGF - D	+
Visfatin	+ (data)
Vitronectin	+
WIF-1	+
WISP-1	+
WISP-3	+
WNT-1	+
WNT-3A	+ (data)	+ (data)
WNT-5A	+
WNT-7A	+ (data)
WNT-9A	+ (data)

If you need a bioassay that is not currently available on our list,
please contact us, and we will be happy to assist you.

We Offer the Most Comprehensive Cytokine and Chemokine Assay Capabilities Worldwide

Most of these assays employ a colorimetric method of measuring cell activity using a non-radioactive substrate, which is equivalent to the 3H-thymidine incorporation assay*.

With diverse experience in large molecule, we are routinely developing new cell-based assays for our customers. We assure strict confidentiality, superior execution, competitive pricing, and a quick turnaround time. The average timeframe for an established assay is few weeks. SBH Sciences is determined to maintain the highest standards and deliver quality products and services. We welcome your suggestions and encourage you to communicate with us about your specific cell-based assay and research requirements.

*Cell Signaling Applications Guide, Promega Corporation

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