Cell Culture Services

Our cell-culture services include cell line development, characterization, and expansion, as well as the development and purification of cell culture-based products.

SBH Sciences has developed over 70 cell culture-derived products, including recombinant cytokines, glycosyltransferases, and anti-cytokine/anti-carbohydrate monoclonal antibodies.

SBH can provide:

• Development of cell lines for cell-based assays
• Growth optimization and characterization of new and existing cell lines
• Scale-up and cryopreservation
• Culture of mammalian and insect cells in multiple formats including roller bottles and spinner flasks
• Serum-free media optimization
• Adaptation to suspension
• Production of lysates
• Increased protein expression in existing cell lines
• Transient and stable mammalian cell transfection, cloning and sub-cloning
• Protein purification and mid-scale production

We are a leading provider of recombinant cytokines including; Activin-A, HGF, IL-23, BMP-2, IFN-β, sIL-6R, BMP-7, and IL-12.

SBH Sciences is the only commercial source of human GDF-15/MIC-1.

Related discovery research services include:

• Detection and quantification of cell culture-derived products (ELISA, HPLC)
• Screening for biological or cytotoxic activity (cell-based bioassays, receptor-based binding assays, or custom-designed assays)
• Formulation and stability studies (e.g., temperature and matrix effect)
• Development of ADA (Anti-Drug Antibody assays)

Let us help you:

• Streamline your production process
• Reduce your development time
• Increase your yields while maintaining exceptional purity
• Reduce production costs