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Cell Culture
We have established ourselves as a premier supplier of high quality reagents for the biomedical industry. SBH Sciences' experience and technical expertise has enabled us to commercially produce highly purified:
Cytokines
Enzymes
Monoclonal Antibodies
- Anti-Cytokine
- Anti-Carbohydrate
We have developed in-house over 70 cell-culture-derived products including; 30 recombinant cytokines, 8 enzymes, and are an industry source for:
Activin-a |
HGF |
IL-23 |
BMP-2 |
IFN-b |
sIL-6R |
BMP-7 |
IL-12 |
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In addition, SBH Sciences produces highly pure naturally expressed human MIC-1 which is available for the R&D market. SBH Sciences' human GDF-15/MIC-1 is a soluble disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains (25,000 MW). SBH Sciences is looking for partners to investigate human MIC-1 as a therapeutic agent, as well as a diagnostic tool.
We specialize in:
Protein Expression, Purification, and Mid-scale Production
- Cell culture of mammalian and insect cells, serum-free media optimization, adaptation to suspension, production of lysates
- Transient and stable mammalian cell transfection, cloning, sub-cloning
- Follow clients SOP's for expression of their product
- Manipulation of customers cell line to improve expression
- Capability to work with mammalian or insect cells in roller bottles or spinner flasks
We offer a broad range of discovery research services including:
- production and purification of biologics (Cell Culture, Protein Purification)
- detection and quantification of these substances (ELISA, HPLC)
- screening for biological or cytotoxic activity (cell-based bioassays, Receptor-based binding assay, or custom designed assays)
- Formulation and stability studies (e.g. temperature and matrix effect)
- Development of ADA (Anti-Drug Antibody assay)
Let us help you:
- Streamline your process
- Reduce your development time
- Increase your yields while maintaining exceptional purity
- Reduce production costs
SBH Sciences welcomes inquiries from those seeking a dependable resource and collaborator in developing pharmaceutical and biotechnology-derived products.
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