Cell Culture

We have established ourselves as a premier supplier of high quality reagents for the biomedical industry. SBH Sciences' experience and technical expertise has enabled us to commercially produce highly purified:

Cytokines

• Recombinant proteins

Enzymes

• Glycosyltransferase

Monoclonal Antibodies

• Anti-Cytokine
• Anti-Carbohydrate

We have developed in-house over 70 cell-culture-derived products including; 30 recombinant cytokines, 8 enzymes, and are an industry source for:

Activin-a	HGF	IL-23
BMP-2	IFN-b	sIL-6R
BMP-7	IL-12

In addition, SBH Sciences produces highly pure naturally expressed human MIC-1 which is available for the R&D market. SBH Sciences' human GDF-15/MIC-1 is a soluble disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains (25,000 MW). SBH Sciences is looking for partners to investigate human MIC-1 as a therapeutic agent, as well as a diagnostic tool.

We specialize in:
Protein Expression, Purification, and Mid-scale Production

• Cell culture of mammalian and insect cells, serum-free media optimization, adaptation to suspension, production of lysates
• Transient and stable mammalian cell transfection, cloning, sub-cloning
• Follow clients SOP's for expression of their product
• Manipulation of customers cell line to improve expression
• Capability to work with mammalian or insect cells in roller bottles or spinner flasks

We offer a broad range of discovery research services including:

• production and purification of biologics (Cell Culture, Protein Purification)
• detection and quantification of  these substances (ELISA, HPLC)
• screening for biological or cytotoxic activity (cell-based bioassays, Receptor-based binding assay, or custom designed assays)
• Formulation and stability studies (e.g. temperature and matrix effect)
• Development of ADA (Anti-Drug Antibody assay)

Let us help you:

• Streamline your process
• Reduce your development time
• Increase your yields while maintaining exceptional purity
• Reduce production costs